disable

To render unable; to take away an ability of, as by crippling.

(chiefly of a person) To impair the physical or mental abilities of; to cause a serious, permanent injury.

“Falling off the horse disabled him.”

To deactivate, to make inoperational (especially of a function of an electronic or mechanical device).

“The pilot had to disable the autopilot of his airplane.”

Lacking ability; unable.