senescence

noun

1. 1

   The state or process of ageing, especially in humans; old age.

2. 2

   Ceasing to divide by mitosis because of shortening of telomeres or excessive DNA damage.

3. 3

   Old age; accumulated damage to macromolecules, cells, tissues and organs with the passage of time.

4. 4

   Fruit senescence, leading to ripening of fruit.

5. 5

   (of a cell) Condition when the cell ceases to divide.