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Cd40

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WordDefinition
ligandnoun(inorganic chemistry, organic chemistry, physical chemistry) A molecule or moiety (ion, functional group, or radical) that binds to another chemical entity to form a larger complex; as, especially:
cd38nounglycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B lymphocytes and natural killer cells, functioning in cell adhesion, signal transduction and calcium signaling
cd43nouna transmembrane cell-surface sialoglycoprotein on certain immune cells, defective in Wiskott-Aldrich syndrome
cd45nounenzyme involved in the regulation of signal transduction in hematopoiesis; used histologically to differentiate between lymphomas and carcinomas
cd33nouna transmembrane receptor expressed on blood cells of myeloid lineage, though also found on some lymphoid cells
cd18nouna protein forming membrane-bound complexes with CD11s, its lack causing leukocyte adhesion deficiency, and also occurring in a soluble form which plasma levels are inversely correlated with disease activity in spondyloarthritis.
cd79anouna protein forming part of the B-cell antigen receptor (BCR), associated with agammaglobulinemia-3
cd11anouna protein part of lymphocyte function-associated antigen 1 and so involved in cellular adhesion and costimulatory signaling in the human immune system.
cd20nouna glycosylated phosphoprotein expressed on all stages of B cell development except the first and last
cd11bnounthe alpha protein subunit that forms with CD18 the heterodimeric integrin macrophage-1 antigen (Mac-1) also known as complement receptor 3 (CR3), present on the surface of many leukocytes involved in the innate immune system
cd10nouna zinc-dependent metalloprotease, expressed in a wide variety of tissues, especially in kidney and on pre-B lymphocytes
cd103noun(strict sense) a protein binding integrin beta 7 to form a heterodimeric; used in identifying hairy cell leukemia and enteropathy-associated T cell lymphoma
cd19nounprotein found on the surface of most B-cells, associating with the B-cell receptor complex
cd15nouna carbohydrate adhesion molecule that can be expressed on glycoproteins, glycolipids and proteoglycans, mediating phagocytosis and chemotaxis; used as a marker in mostly hematologic malignancies
cd30nouna cell membrane protein of the tumor necrosis factor receptor family, serving as a tumor marker and the target of brentuximab vedotin
cd23nouna C-type lectin acting as receptor for IgE, found on mature B cells, activated macrophages, eosinophils, follicular dendritic cells, and platelets
cluster of differentiationnoun(countable, immunology) A cell surface molecule used as a marker in this protocol.
cd46nouna membrane protein acting as an inhibitory complement receptor, being port-of-access for measles, human herpesvirus-6 and Neisseria.
cd22nouna molecule found on the surface of mature B cells and to a lesser extent on some immature B cells, helping to prevent the overactivation of the immune system and the development of autoimmune diseases
cd135nouna proto-oncogene, mutations possibly leading to acute myelogenous leukemia (AML) and carrying an adverse prognosis.

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